Gender, politics and everyday life get skewered in this unusual documentary featuring four lesbian stand-up comics who've blazed a trail since the 1980s: Kate Clinton, Karen Williams, Marga Gomez and Suzanne Westenhoefer. Included is footage from some of their best shows, along with side-by-side interviews with each of the performers as they discuss their approach to comedy and what it's like to be openly gay in the comedy circuit.

Director Spike Lee takes on the big, bad world of love and business. When John (Anthony Mackie) blows the whistle on his corrupt bosses at the biotech company where he works, he touches off a maelstrom of investigations headed by the Securities and Exchange Commission and winds up jobless. But when his ex-girlfriend (Kerry Washington) pays him to get her and her lesbian lover (Dania Ramirez) pregnant, he may have found his new calling.

This riveting documentary traces the experiences of filmmaker Pam Walton as she struggles to reunite with her "family values" father after a long-standing rift. Rus Walton -- a radical religious fundamentalist -- disowned his daughter because of her lesbian lifestyle. Although he once suggested that practicing homosexuals should be executed, Pam is willing to pay the emotional price to fulfill her longing for parental acceptance.

Deepa Mehta's Fire, the first Indian film about lesbians, follows two Hindu women struggling with loveless, arranged marriages. When Sita (Nandita Das) discovers that her husband, Jatin (Javed Jaffrey), has a mistress, she shares her unhappiness with her sister-in-law, Radha (Shabana Azmi), who cannot give birth. As the lukewarm coals of their long-term relationships fade, they ignite passion in their lives by finding comfort in each other.

Two hot-button issues -- homosexuality and religion -- are thrust together in this revealing documentary by Sandi Simcha Dubowski. Gay and lesbian Jews who have been cast off by their families and by religious figures are interviewed in major metropolitan areas across the globe. Even in societies where homosexuality is gaining acceptance, many of those interviewed still struggle with balancing an intolerant faith with their sexual orientation.

Treasure Lee (Yolonda Ross) is a bad girl on the move out of "juvenile" and into the state penitentiary. There, she befriends Brownie (Davenia McFadden), a badass lifer who keeps her hand in dealing drugs and contraband, using an "extended family" of loyal girls who swear their undying allegiance to the cell-block mama. But Brownie's charisma shields a malevolence that just might put Treasure in harm's way.

In this love-crazed comedy, commitment phobic Allegra (Elizabeth Reaser) is recovering from a breakup with her girlfriend but begins questioning her sexuality and sanity when she falls for a member of the opposite sex. Philip (Justin Kirk) is the tidy professor who romances the ambivalent Allegra while she also pursues Grace (Gretchen Mol), a straight, recently single woman. Director Maria Maggenti is the force behind this snappy screwball romp.

Four high-school girls' lives are changed forever when a defiant but charismatic drifter (Angelina Jolie) unites them and inspires them to exact revenge on their sexually abusive biology teacher. The quintet then spirals toward anarchy as they abduct and blackmail the father of one of the girls -- an act they come to rue when they find themselves on the lam and battling for their survival. Loosely based Joyce Carol Oates' controversial novel.

Teena Brandon (Hilary Swank) moves to a small Nebraska town in search of a new life. Preferring to cross-dress and taking the name Brandon Teena, she passes herself off as a boy, begins dating Lana (Chloe Sevigny) and makes friends among the town's redneck men ... until the truth is revealed. Swank's Oscar-winning portrayal of this real-life character illuminates one woman's voyage of self-discovery -- and the events that cut it short.

In this adaptation of Fanny Flagg's novel, flashbacks reveal the remarkable and mysterious story of soul mates Idgie (Mary Stuart Masterson) and Ruth Jamison (Mary-Louise Parker), whose antics cause an uproar in their rural Southern town during the 1920s. Feisty Ninny Threadgoode (Jessica Tandy) tells the tale to a repressed Alabama housewife (Kathy Bates), who becomes obsessed with Idgie and Ruth, and ultimately finds inspiration in their story.

When wealthy 19th-century socialite Margaret Prior (Anna Madeley) tries to find purpose in her life by volunteering at a women's prison, she becomes obsessed with one inmate (Zoe Tapper) whose gifts for the paranormal hold a special attraction. Soon, she's embroiled in an eerie world of secret desires she never dreamed possible. Tim Fywell directs this drama based on the mystery novel by Sarah Waters.

Melissa Etheridge narrates this documentary that explores the progress and challenges of the post-Stonewall lesbian/gay rights movement through archival footage and interviews with leaders such as Barbara Gittings, Armistead Maupin, Jewelle Gomez and Dorothy Allison. The film chronicles key events from 1970 to the end of the 20th century, including sexual liberation, conflicts with the feminist movement, AIDS and political organization.